FDA Approves Genetically Altered Pigs Meant To Prevent Meat Allergies From Triggering

The FDA has given the green light to the usage of “GalSafe” pigs, a genetically engineered variety that is designed to prevent meat allergies from getting triggered when consuming pork.

GalSafe pigs were developed by biomedical firm Revivicor, who received the first-ever joint approval for their pigs in both food and medical uses. This means that in the future, we could see these pigs both being consumed and used in place of standard pork cells in current medical treatments.

Red meat allergies can be triggered by contracting “Alpha-gal Syndrome,” which is a condition that causes us to react to a specific sugar called “Alpha-gal” that is common in many mammals (excluding humans). These allergic reactions can range from mild to severe.

Alpha-gal Syndrome is believed to be transmitted via the bite of the Lone Star tick, but more research needs to be done to determine the role that the ticks play there.

Photo: Shutterstock

These GalSafe pigs have been genetically engineered to have the Alpha-gal sugar removed, preventing those with Alpha-gal Syndrome from getting an allergic reaction when eating meat from these specific animals. They would also not get these allergic reactions from any medicines developed with cells from these specific pigs.

Revivicor’s safety studies focused on the potential for allergic reactions to occur in medicinal uses of the GalSafe pig cells. The FDA also reviewed the safety of consuming pork from these pigs, and determined they would also be safe to eat, finding that the Alpha-gal sugar was removed across multiple generations of pigs. However, safety of eating was not evaluated for those with Alpha-gal syndrome, meaning that more research needs to be done there before confirming that those with meat allergies can eat the pork with full confidence.

For those concerned about any potential danger of eating genetically engineered foods, it should be noted that there is a global consensus from scientists that such foods are safe to eat.

The FDA also found that the pigs were no more environmentally harmful or at risk of a food safety outbreak than standard pigs. GalSafe pigs have more stringent living conditions than standard pigs, so if anything, they might be getting slightly better care.

While GalSafe pigs have been approved to eat, it may take a while before pork products from these pigs start becoming available for sale. These are just the second-ever genetically engineered animal approved for eating, after AquAdvantage salmon, a product still not available for purchase yet.

When it is available, however, Revivicor has indicated that they intend to sell it by mail order, not through grocery stores.

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